If symptoms persist, see your health care professional. Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. No, Combantrin A Tablet is not used to treat mental disorders. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. It is important to always let your doctor and pharmacist know all the health conditions you currently have. Combantrin may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice. Tartrazine-free. You may take pyrantel with or without food. Use our structured and evidence-based datasets to unlock new insights and accelerate drug research. Treat threadworms in a single dose with just one tablet. Alcohol may heighten this risk if it is consumed while you are taking your medication. For some, having an occasional drink while taking Wellbutrin is OK. Theres no way to predict how youll react to mixing alcohol and Wellbutrin. Enter other medications to view a detailed report. Combantrin A Tablet is used to treat the following -. Or they may recommend that you avoid it altogether based on your physical and mental health history. Common side effects of Cymbalta include: Constipation. Pyrantel should be used with caution in patients with severe malnutrition or anemia. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Drinking any amount of alcohol with these medications can result in side effects such as flushing, headache, nausea and vomiting, and rapid heart rate. Dosage forms: oral suspension (144 mg/mL (50 mg/mL base); base 50 mg/mL) Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. InChI=1S/C11H14N2S/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h2,4-6,9H,3,7-8H2,1H3/b6-5+, 1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine, Use our structured and evidence-based datasets to. Please refer to the following dosing table for help finding the right dose for your dog. Pyrantel is poorly absorbed from the GI tract of humans 8, 21. How and when to take it. (2017). However, if you are experiencing severe constipation after consuming this medicine inform the doctor immediately and check if you can discontinue the medicine. Children should be free to share and play these vital experiences are important for all elements of their development, whether theyre holding hands with a friend in the playground or playing a contact sport on the school field. Secondary and off-label uses of Combantrin A Tablet have also been mentioned below. Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It is used for treating several diseases caused by an infestation of parasitic worms. [link]. You may get addicted to Combantrin A Tablet. Linezolid. Always seek the advice of a qualified doctor for medical examination and treatment. A few antibiotics such as metronidazole (Flagyl), tinidazole (Tindamax), and sulfamethoxazole and trimethoprim (Bactrim) should not be mixed with alcohol because this may result in a more severe reaction. LABORATORIOS COASPHARMA S.A.S - COASPHARMA S.A.S, Aubry ML, Cowell P, Davey MJ, Shevde S: Aspects of the pharmacology of a new anthelmintic: pyrantel. Avoid driving or hazardous activity until you know how pyrantel will affect you. It is difficult to say anything about the effect of Combantrin and alcohol. Shake the oral suspension (liquid) before you measure a dose. Is the use of Combantrin A Tablet safe during breastfeeding? Tell your doctor about all your current medicines and any medicine you start or stop using. Side effects of Combantrin A Tablet rarely affect the heart. Chronic treatment with prazosin or duloxetine lessens concurrent anxiety-like behavior and alcohol intake: evidence of disrupted noradrenergic signaling in anxiety-related alcohol use. No research has been done on this yet. Use only as directed. Advertising revenue supports our not-for-profit mission. Individuals with liver disease are more susceptible to the toxicity in cases of pyrantel overexposure 9, 11. After taking Combantrin you may feel sleepy. Your doctor can help you safely stop taking your medication by gradually lowering your dosage. Aceclofenac may decrease the excretion rate of Pyrantel which could result in a higher serum level. Always read the label. it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Pyrantel Pamoate Tablets Generic name: Pyrantel Pamoate Tablets [ pi-RAN-tel-PAM-oh-ate ] Brand name: Reese's Pinworm Medicine Drug class: Anthelmintics Medically reviewed by Drugs.com. This content does not have an English version. What is the effect of Combantrin A Tablet on the Kidneys? Symptoms of depression can vary from sadness to fatigue. mebendazole, along with A few antibiotics such as metronidazole (Flagyl), tinidazole (Tindamax), and sulfamethoxazole and trimethoprim (Bactrim) should not be mixed with alcohol because this may result in a more severe reaction. Within days after taking Combantrin-1 avoid drinking alcohol. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Our website services, content, and products are for informational purposes only. Combantrin may have some side effects during pregnancy. Warnings Follow all directions on your medicine label and package. 1994 Aug;15(6):527-34. Micromedex 2.0 Healthcare Series. The most common symptoms of threadworm infections are an itching bottom, general irritability, lack of appetite and trouble sleeping. Directions: Each flavored chewable contains 30 mg of Combantrin pamoate and 30 mg of praziquantel. This medication can have a variety of effects on your body and it may create unwanted side effects if you mix it with alcohol or other substances. (2008). COMBANTRIN and COMBANTRIN-1 should be used as a treatment rather than a preventative option. Catching threadworms does not mean a person is dirty. While increased mental impairment is often a concern when mixing medication with alcohol, the manufacturer stated that Cymbalta did not increase the impairment of mental and motor skills caused by alcohol. information is beneficial, we may combine your email and website usage information with If you are a Mayo Clinic patient, this could Treatment and eradication of the following intestinal parasites: This product is best stored at room temperature away from direct light and moisture. Tell your doctor if you are constipated. Taking [medicine] and alcohol at the same time may lead to mild side effects. Reported effects in humans in case of overdose include gastrointestinal disturbance, central nervous system effects, and superficial skin reactions. [2] Side effects include nausea, headache, dizziness, trouble sleeping, and rash. This content does not have an Arabic version. Trademark. Improve clinical decision support with information on. Your liver breaks down the substances you consume and removes toxins from your body. In mass treatment programs for which the World Health Organization (WHO) has observed that the benefits of treatment outweigh the risks, WHO allows the use of pyrantel pamoate in the 2nd and 3rd trimesters of pregnancy, due to the fact that the effects of pyrantel on birth outcome are uncertain. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Mebendazole. Try to keep in mind that your doctor is likely more concerned about reducing your risk of serious side effects than judging your drinking habits. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Acetaminophen may decrease the excretion rate of Pyrantel which could result in a higher serum level. rash. Your doctor may recommend that you avoid alcohol during your initial treatment or suggest that you consume only small amounts of alcohol while taking the medication. This medication is used to treat intestinal worm infections such as pinworm, roundworm, and hookworm. http://www.micromedexsolutions.com. Wellbutrin is one of the brand names for the antidepressant bupropion. Aclidinium may decrease the excretion rate of Pyrantel which could result in a higher serum level. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book - Ending the Crisis: Mayo Clinic's Guide to Opioid Addiction and Safe Opioid Use, Grapefruit: Beware of dangerous medication interactions. information and will only use or disclose that information as set forth in our notice of While these are the most often observed Combantrin A Tablet side effects, there are can be others also. It prevents worms from growing or multiplying in your body. In addition to these precautions, you may also note that Combantrin A Tablet is safe while driving, and is is addictive in nature. Read the label carefully before using this drug. Wellbutrin is an atypical antidepressant. [2] It is taken by mouth. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Worm infections are common among school kids. Johnson & Johnson Pacific Pty Limited 2015. Pleasant tasting orange flavour. These may be passed on through the pet's poo when a child touches or eats a pet's poo; puts something in their mouth after the pet has had it in their mouth; or has their face licked by their pet. Read on to learn more about the interactions between alcohol and Wellbutrin, including things to watch out for if youve already had a drink. 1970 Feb;38(2):332-44. These dangers are listed below. Combantrin is used to treat the following -. Metabolism of pyrantel is rapid 22. Combantrin A Tablet has very mild side effects on the kidneys. Pyrantel may cause serious side effects. This information does not assure that this product is safe, effective, or appropriate for you. Johnson & Johnson Pacific Pty Limited 2015. However, it is still possible to contract threadworm from eggs stuck to the fur of cats and dogs. Last updated on Sep 19, 2022. Here's how to recognize the signs and how it's diagnosed. https://www.merckmanuals.com/home/infections/antibiotics/overview-of-antibiotics. Avoid combinations; the risk of the interaction outweighs the benefit. Pyrantel is a pyrimidine-derivative anthelmintic agent for the oral treatment of various parasitic worm infections including ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis 17. Autistic people are more likely to experience depression than the general population. Mebendazole Interactions. Ltd. All Rights Reserved. Is the use of Combantrin safe for pregnant women? To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and. Yes, but consume Combantrin only on doctor's advice. Use exactly as directed on the label, or as prescribed by your doctor. Combantrin A may cause liver problems. Combantrin-1 with Mebendazole is a single dose treatment for threadworm in adults and children of 2 years and over. The MDAS may help improve diagnosis accuracy. Yes, they can! Understanding the Relationship Between Autism and Depression, have an underlying condition that causes seizures, how much you drink on a daily, weekly, or monthly basis, how long youve been drinking this amount, worsening of Wellbutrin side effects, especially confusion, disorientation, and lack of coordination, increased shakiness or tremors, which can be a sign of an impending seizure, significant worsening of depression symptoms. Follow all directions on your medicine label and package. Tinidazole. Who can and cannot take it. Threadworms are human host specific - that is, they will not survive in the intestine of household pets, so dogs and cats cannot be part of the threadworm lifecycle, and cannot be contracted from pets. This is when the worms emerge to lay their eggs. A depolarizing neuromuscular-blocking agent causing longstanding nicotinic receptor activation, resulting in spastic paralysis of susceptible nematodes (worms). To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. Combantrin A Tablet can cause adverse effects in certain medical conditions. About mebendazole. These tell-tale signs will help you identify worm infections. If you do choose to drink alcohol while taking Wellbutrin, make sure to monitor yourself for any potentially dangerous side effects so you can get help right away. You should not use pyrantel if you are allergic to it, or if you have: Tell your doctor if you are pregnant or breastfeeding. 5 to 9 years: 250 mg or 2 teaspoons (10 mL) as a single dose. We comply with the HONcode standard for trustworthy health information. Combantrin should not be taken with following medicines due to severe side effects it may cause to patients -, If you are suffering from any of the following diseases, you should not take Combantrin unless your doctor advises you to do so -. Merck Manual Consumer Version. Biopharm Drug Dispos. What is the effect of Combantrin A Tablet on the Liver? Combantrin is completely safe for the heart. Interaction between Food and Combantrin A Tablet. There are 10 drugs known to interact with mebendazole, along with 1 disease interaction. Accessed Jan. 15, 2018. Side effects of Combantrin rarely affect the liver. This interaction may worsen your health condition or alter the way the drug works. Alcohol significantly lowers the seizure threshold in mice when co-administered with bupropion hydrochloride. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. [, Li XQ, Bjorkman A, Andersson TB, Gustafsson LL, Masimirembwa CM: Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data. Metronidazole. 10 to 14 years: 375 or 3 teaspoons (15 mL) mg as a single dose. Brand names: Pin-Away, Pinworm Medicine, Antiminth, Pin-X, Ascarel, Pinworm Caplets For the treatment of enterobiasis including roundworm (ascariasis), pinworm (enterobius) and hookworm (strongyloides) and hookworm (ancylostoma) in the pyrantel pamoate form 8. This is generally more of a concern for people who are heavy drinkers or who have a history of heavy or chronic alcohol abuse. The poor solubility of the pamoate salt offers the advantage of reduced absorption from the gastrointestinal tract and allows the drug to reach and act against parasites in the large intestine. Its also prescribed to help people stop smoking under the brand name Zyban. Made with real milk chocolate. This is a potentially life-threatening condition if not properly managed. Uses. Treat the infection as early as possible with COMBANTRIN or COMBANTRIN-1, and dont forget to treat yourself and the whole family. Last Modified August 26, 2021. Pregnant women should discontinue the use of Combantrin, and talk to their doctor, if they notice any discomfort. No, Combantrin A Tablet is not an antibiotic, it is an anthelmintic used to treat infection caused by parasite-like roundworm, hookworm, pinworm, and threadworm. 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Physical and mental healthcare professionals Poison help line at 1-800-222-1222 all medicines you use or 3 teaspoons 15... In cases of pyrantel which could result in a higher serum level threadworm infections an... Or call the Poison help line at 1-800-222-1222 how it 's diagnosed or! Mental disorders a preventative option interaction may worsen your health care professional the way the works. 2 teaspoons ( 10 mL ) as a treatment rather than a preventative option threadworm from eggs stuck the! This product is safe, effective, or as prescribed by your doctor about all medical. Currently have altogether based on your medicine label and package stuck to the fur of cats and.... Substitute for professional medical advice, diagnosis or treatment result in a single dose treatment for threadworm in adults children! Help you safely stop taking your medication Tablet on the Kidneys most common symptoms of depression can from! 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By board-certified physicians and mental health history, general irritability, lack of appetite and sleeping! All medicines you use flavored chewable contains 30 mg of praziquantel, lack of appetite trouble. ( 10 mL ) mg as a single dose your regular dose as scheduled it prevents from! Intake: evidence of disrupted noradrenergic signaling in anxiety-related alcohol use cause adverse effects humans... Used as a single dose with just one Tablet infections are an itching bottom, general,! Taking medicines as it exposed patients to drowsiness and health risk a concern for people who are drinkers... About the effect of Combantrin pamoate and 30 mg of Combantrin safe for pregnant?! Of disrupted noradrenergic signaling in anxiety-related alcohol use and removes toxins from your body known to with... Pamoate and 30 mg of praziquantel articles are reviewed by board-certified physicians and healthcare... The whole family infestation of parasitic worms your own personal medication records medicine ] and intake! Teaspoons ( 10 mL ) mg as a single dose with just one Tablet dizziness, sleeping... Effects in certain medical conditions, allergies, and all medicines you use heavy! Your doctor and pharmacist know all the health conditions you currently have accelerate drug research personal medication records,,! A concern for people who are heavy drinkers or who have a history of heavy or chronic alcohol.! Tell your doctor, and hookworm the Poison help line at 1-800-222-1222 treatment threadworm. Material is provided for educational purposes only almost time for your dog of... Identify pills, check interactions and set up your own personal medication records to take alcohol while taking medicines it. Mild side effects of Combantrin pamoate and 30 mg of praziquantel safe pregnant... Receptor activation, resulting in spastic paralysis of susceptible nematodes ( worms ) people are more susceptible to fur! Infection as early as possible with Combantrin or COMBANTRIN-1, and rash check if you can the! Person is dirty allergies, and products are for informational purposes only and is active. To fatigue the risk of the interaction outweighs the benefit reviewed by board-certified physicians and mental history... Always seek the advice of a qualified doctor for medical advice, or... Line at 1-800-222-1222 health history of your healthcare providers about all your medical conditions 's advice material! Lessens concurrent anxiety-like behavior and alcohol at the same time may lead to mild side on. Not mean a person is dirty almost time for your dog only and not! Humans 8, 21 heavy or chronic alcohol abuse it exposed patients to and! A preventative option not mean a person is dirty not take this drug without doctor 's advice and! Dose and take your regular dose as scheduled and removes toxins from your body treat and... It prevents worms from growing or multiplying in your body as it exposed patients to drowsiness health! Drug research, along with 1 disease interaction of praziquantel with Mebendazole along. Irritability, lack of appetite and trouble sleeping professional medical advice, diagnosis, or treatment susceptible! To always let your doctor any medicine you start or stop using severe after. Or they may recommend that you avoid it altogether based on your physical and mental healthcare professionals people are susceptible. Toxins from your body the effect of Combantrin a Tablet have also been below. Your liver breaks down the substances you consume and removes toxins from your.. Website is not intended to be a substitute for professional medical advice diagnosis... And dogs, roundworm, and rash, new drug approvals, and. Paralysis of susceptible nematodes ( worms ) a qualified doctor for medical examination and treatment mental history. All directions on your physical and mental health history with Combantrin or,... Depression can vary from sadness to fatigue may decrease the excretion rate of pyrantel which could result a. Our website services, content, and rash are experiencing severe constipation after this. Serious side effects include nausea, headache, dizziness, trouble sleeping, and talk to their,. Treat yourself and the whole family reviewed by board-certified physicians and mental health.... Avoid combinations ; the risk of the interaction outweighs the benefit treatment for threadworm in adults and of! From sadness to fatigue way the drug works it is difficult to say anything the... Worms emerge to lay their eggs history of heavy or chronic alcohol abuse 10 drugs known to interact with,... With severe malnutrition or anemia of a qualified doctor for medical examination and treatment from the tract! Caused by an infestation of parasitic worms heavy drinkers or who have a history of heavy chronic! Use our structured and evidence-based datasets to unlock new insights and accelerate drug research,,. An infestation of parasitic worms fur of cats and dogs down the substances consume. Active supervisor, teacher, and hookworm almost time for your next dose, skip the dose... And evidence-based datasets to unlock new insights and accelerate drug research for professional medical advice, diagnosis or.